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1

New classes of antibiotics

Moir, Donald T, Opperman, Timothy J, Butler, Michelle M, Bowlin, Terry L

Journal:

Current Opinion in Pharmacology

Year:

2012

Language:

english

File:

PDF, 1.10 MB

english, 2012

2

Efflux-mediated bis-indole resistance in Staphylococcus aureus reveals differential substrate specificities for MepA and MepR

Timothy J. Opperman, John D. Williams, Chad Houseweart, Rekha G. Panchal, Sina Bavari, Norton P. Peet, Donald T. Moir, Terry L. Bowlin

Journal:

Bioorganic & Medicinal Chemistry

Year:

2010

Language:

english

File:

PDF, 488 KB

english, 2010

3

Dimerization of the UmuD' protein in solution and its implications for regulation of SOS mutagenesis

Ferentz, Ann E., Opperman, Timothy, Walker, Graham C., Wagner, Gerhard

Journal:

Natural Structural Biology

Year:

1997

File:

PDF, 677 KB

1997

4

Mutational Analysis and Secondary Structure Model of the RNP1-like Sequence Motif of Transcription Termination Factor Rho

Asuncion Martinez, Timothy Opperman, John P. Richardson

Journal:

Journal of Molecular Biology

Year:

1996

Language:

english

File:

PDF, 405 KB

english, 1996

5

The ts 15 mutation of Escherichia coli alters the sequence of the C-terminal nine residues of Rho protein

Timothy Opperman, Asuncion Martinez, John P. Richardson

Journal:

Year:

1995

Language:

english

File:

PDF, 146 KB

english, 1995

6

Reconstruction of Canine Mandibular Bone Defects Using a Bone Transport Reconstruction Plate

Elsalanty, Mohammed E., Zakhary, Ibrahim, Akeel, Sara, Benson, Byron, Mulone, Timothy, Triplett, Gilbert R., Opperman, Lynne A.

Journal:

Annals of Plastic Surgery

Year:

2009

Language:

english

File:

PDF, 1.09 MB

english, 2009

7

Design, synthesis and activities of 4/5-acyl-2-aminoimidazolyl analogues of oroidin for biofilm inhibition

Rasapalli, Sivappa, Dhawane, Abasaheb, Rees, Christiaan, Golen, James A., Singh, Bal Ram, Cai, Shuowei, Jasinski, Jerry, Kwasny, Steven M., Moir, Donald T., Opperman, Timothy J., Bowlin, Terry L.

Journal:

Year:

2013

Language:

english

File:

PDF, 622 KB

english, 2013

8

Detour of prenostodione synthesis towards pyrazolones for antibacterial activity

Rasapalli, Sivappa, Fan, Yingjun, Yu, Menglong, Rees, Christiaan, Harris, John T., Golen, James A., Jasinski, Jerry P., Rheingold, Arnold L., Kwasny, Steven M., Opperman, Timothy J.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2013

Language:

english

File:

PDF, 626 KB

english, 2013

9

Potent and broad-spectrum antibacterial activity of indole-based bisamidine antibiotics: Synthesis and SAR of novel analogs of MBX 1066 and MBX 1090

Williams, John D., Nguyen, Son T., Gu, Shen, Ding, Xiaoyuan, Butler, Michelle M., Tashjian, Tommy F., Opperman, Timothy J., Panchal, Rekha G., Bavari, Sina, Peet, Norton P., Moir, Donald T., Bowlin, T

Journal:

Bioorganic & Medicinal Chemistry

Year:

2013

Language:

english

File:

PDF, 5.73 MB

english, 2013

10

A Model for a umuDC-Dependent Prokaryotic DNA Damage Checkpoint

Timothy Opperman, Sumati Murli, Bradley T. Smith and Graham C. Walker

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.28 MB

english, 1999

11

The Escherichia coli SOS Mutagenesis Proteins UmuD and UmuD′Interact Physically with the Replicative DNA Polymerase

Mark D. Sutton, Timothy Opperman and Graham C. Walker

Journal:

Proceedings of the National Academy of Sciences

Year:

1999

Language:

english

File:

PDF, 1.22 MB

english, 1999

12

Lack of Alternative mRNA Splicing Leads to Midgut-Specific Expression of a Single High-Affinity$\text{BT}-\text{R}_{1}$Receptor in Manduca sexta

Autumn K. Hass, Heather M. Fox, Laura J. Opperman and Timothy P. Keeton

Journal:

Year:

2005

Language:

english

File:

PDF, 1.62 MB

english, 2005

13

Dentate Transport Discs Can Be Used to Reconstruct Large Segmental Mandibular Defects

Elsalanty, Mohammed E., Malavia, Veera, Zakhary, Ibrahim, Mulone, Timothy, Kontogiorgos, Elias D., Dechow, Paul C., Opperman, Lynne A.

Journal:

Journal of Oral and Maxillofacial Surgery

Year:

2015

Language:

english

File:

PDF, 2.86 MB

english, 2015

14

Structure–activity relationships of a novel pyranopyridine series of Gram-negative bacterial efflux pump inhibitors

Nguyen, Son T., Kwasny, Steven M., Ding, Xiaoyuan, Cardinale, Steven C., McCarthy, Courtney T., Kim, Hong-Suk, Nikaido, Hiroshi, Peet, Norton P., Williams, John D., Bowlin, Terry L., Opperman, Timothy

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.18 MB

english, 2015

15

TAOK3 phosphorylates the methylenecyclopropane nucleoside MBX 2168 to its monophosphate

Komazin-Meredith, Gloria, Cardinale, Steven C., Comeau, Katelyn, Magalhaes, Kevin J., Hartline, Caroll B., Williams, John D., Opperman, Timothy J., Prichard, Mark N., Bowlin, Terry L.

Journal:

Antiviral Research

Year:

2015

Language:

english

File:

PDF, 491 KB

english, 2015

16

Comparing the conservation effectiveness of private water transactions and public policy reforms in the conserving California landscapes initiative

Duane, Timothy P., Opperman, Jeff J.

Journal:

Year:

2010

Language:

english

File:

PDF, 11.56 MB

english, 2010

17

Research Article: Lack of alternative mRNA splicing leads to midgut-specific expression of a single high-affinity BT-R 1 receptor in Manduca sexta

Hass, Autumn K., Fox, Heather M., Opperman, Laura J., Keeton, Timothy P.

Journal:

Year:

2005

Language:

english

File:

PDF, 162 KB

english, 2005

18

Synthesis and antifungal evaluation of head-to-head and head-to-tail bisamidine compounds

Nguyen, Son T., Kwasny, Steven M., Ding, Xiaoyuan, Williams, John D., Peet, Norton P., Bowlin, Terry L., Opperman, Timothy J.

Journal:

Bioorganic & Medicinal Chemistry

Year:

2015

Language:

english

File:

PDF, 1.46 MB

english, 2015

19

The discovery of bacterial FASII inhibitors using a novel cellular bioluminescent reporter assay

Wallace, Joselynn, Bowlin, Nicholas O., Mills, Debra M., Saenkham, Panatda, Kwasny, Steven M., Opperman, Timothy J., Williams, John D., Rock, Charles O., Bowlin, Terry L., Moir, Donald T.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2015

Language:

english

File:

PDF, 2.56 MB

english, 2015

20

Microbial pathogen genomes – new strategies for identifying therapeutic and vaccine targets

Opperman, Timothy, Ling, Losee L, Moir, Donald T

Journal:

Expert Opinion on Therapeutic Targets

Year:

2003

Language:

english

File:

PDF, 303 KB

english, 2003

21

Correction of Coronal Suture Synostosis Using Suture and Dura Mater Allografts in Rabbits With Familial Craniosynostosis

Mooney, Mark P., Burrows, Annie M., Smith, Timothy D., Losken, H. Wolfgang, Opperman, Lynne A., Dechant, Jason, Kreithen, Amy M., Kapucu, Rusen, Cooper, Gregory M., Ogle, Roy C., Siegel, Michael I.

Journal:

The Cleft Palate-Craniofacial Journal

Year:

2001

Language:

english

File:

PDF, 531 KB

english, 2001

22

Optimization of a novel series of pyranopyridine RND efflux pump inhibitors

Aron, Zachary, Opperman, Timothy J

Journal:

Current Opinion in Microbiology

Year:

2016

Language:

english

File:

PDF, 1.06 MB

english, 2016

23

DNA Targeting as a Likely Mechanism Underlying the Antibacterial Activity of Synthetic Bis-indole Antibiotics

Opperman, Timothy J., Kwasny, Steven M., Li, Jessica Bo, Lewis, Mark A., Aiello, Daniel, Williams, John D., Peet, Norton P., Moir, Donald T., Bowlin, Terry L., Long, Eric C.

Journal:

Antimicrobial Agents and Chemotherapy

Year:

2016

Language:

english

File:

PDF, 922 KB

english, 2016

24

In Vitro Mechanical Evaluation of Mandibular Bone Transport Devices

Zapata, Uriel, Watanabe, Ikuya, Opperman, Lynne A., Dechow, Paul C., Mulone, Timothy, Elsalanty, Mohammed E.

Journal:

Journal of Medical Devices

Year:

2014

Language:

english

File:

PDF, 1.41 MB

english, 2014

25

Lack of AcrB Efflux Function Confers Loss of Virulence on Salmonella enterica Serovar Typhimurium

Wang-Kan, Xuan, Blair, Jessica M. A., Chirullo, Barbara, Betts, Jonathan, La Ragione, Roberto M., Ivens, Alasdair, Ricci, Vito, Opperman, Timothy J., Piddock, Laura J. V., Davies, Julian E.

Journal:

Year:

2017

Language:

english

File:

PDF, 1.98 MB

english, 2017

26

The hydrophobic trap—the Achilles heel of RND efflux pumps

Aron, Zachary, Opperman, Timothy J.

Journal:

Research in Microbiology

Year:

2017

Language:

english

File:

PDF, 2.31 MB

english, 2017

27

Recent advances toward a molecular mechanism of efflux pump inhibition

Opperman, Timothy J., Nguyen, Son T.

Journal:

Frontiers in Microbiology

Year:

2015

Language:

english

File:

PDF, 4.42 MB

english, 2015

28

Structure–activity exploration of a small-molecule Lipid II inhibitor

de Leeuw, Erik, Fletcher, Steven, Yu, Wenbo, Huang, Jing, Kwasny, Steven, Chauhan, Jay, Opperman, Timothy, MacKerrel, Alexander

Journal:

Drug Design Development and Therapy

Year:

2015

Language:

english

File:

PDF, 1.61 MB

english, 2015

29

Correction of Coronal Suture Synostosis Using Suture and Dura Mater Allografts in Rabbits with Familial Craniosynostosis

Mooney, Mark P., Burrows, Annie M., Smith, Timothy D., Losken, H. Wolfgang, Opperman, Lynne A., Dechant, Jason, Kreithen, Amy M., Kapucu, Rusen, Cooper, Gregory M., Ogle, Roy C., Siegel, Michael I.

Journal:

The Cleft Palate-Craniofacial Journal

Year:

2001

Language:

english

File:

PDF, 522 KB

english, 2001

30

Optimization of a Small-Molecule Lipid II binder

Chauhan, Jay, Kwasny, Steven M., Fletcher, Steven, Opperman, Timothy J., de Leeuw, Erik P.H.

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2019

Language:

english

File:

PDF, 632 KB

english, 2019

31

Optimization of a Benzothiazole Indolene Scaffold Targeting Bacterial Cell Wall Assembly

Chauhan, Jay, Yu, Wenbo, Cardinale, Steven, Opperman, Timothy J, MacKerell Jr, Alexander D, Fletcher, Steven, de Leeuw, Erik PH

Journal:

Drug Design Development and Therapy

Year:

2020

Language:

english

File:

PDF, 1.72 MB

english, 2020

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